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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT5B
All Species:
26.97
Human Site:
S189
Identified Species:
49.44
UniProt:
Q9H1J7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1J7
NP_110402.2
359
40323
S189
E
K
N
F
A
K
G
S
E
E
Q
G
R
V
L
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
K180
D
A
K
E
R
K
G
K
D
A
R
A
L
M
N
Rhesus Macaque
Macaca mulatta
XP_001117880
429
46995
S259
E
K
N
F
A
K
G
S
E
E
Q
G
R
E
I
Dog
Lupus familis
XP_541837
360
40483
S190
E
R
I
H
A
K
G
S
Y
E
S
A
R
I
L
Cat
Felis silvestris
Mouse
Mus musculus
P22726
359
40325
S189
E
K
N
F
A
K
G
S
E
E
Q
G
R
A
L
Rat
Rattus norvegicus
Q9QXQ7
380
42265
S210
E
R
I
H
A
K
G
S
Y
E
S
A
R
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
K181
D
A
K
E
R
K
G
K
D
A
R
A
L
M
N
Chicken
Gallus gallus
P49337
351
38945
A179
V
R
E
R
S
K
G
A
S
S
N
R
A
L
M
Frog
Xenopus laevis
P33945
360
40662
S190
E
K
N
F
P
K
G
S
E
E
Q
A
R
S
L
Zebra Danio
Brachydanio rerio
Q92050
363
41119
S193
E
K
N
Y
P
R
G
S
V
E
H
A
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397473
422
46971
S252
E
R
S
F
K
R
G
S
R
E
Q
G
R
S
L
Nematode Worm
Caenorhab. elegans
P34889
360
40418
N185
K
E
H
D
P
K
R
N
H
D
N
G
R
S
L
Sea Urchin
Strong. purpuratus
XP_779946
415
46408
S245
E
T
N
P
Q
R
G
S
F
A
Y
D
R
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.5
74.1
80.2
N.A.
94.1
76.8
N.A.
48.7
48.1
83.6
79.6
N.A.
N.A.
52.1
45.5
55.6
Protein Similarity:
100
63.3
78.3
89.1
N.A.
97.7
85
N.A.
63.7
62.9
91.1
89.2
N.A.
N.A.
65.6
66.9
68.6
P-Site Identity:
100
13.3
86.6
53.3
N.A.
93.3
53.3
N.A.
13.3
13.3
80
53.3
N.A.
N.A.
60
26.6
33.3
P-Site Similarity:
100
40
93.3
66.6
N.A.
93.3
66.6
N.A.
40
46.6
80
66.6
N.A.
N.A.
80
60
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
39
0
0
8
0
24
0
47
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
0
0
0
0
16
8
0
8
0
0
0
% D
% Glu:
70
8
8
16
0
0
0
0
31
62
0
0
0
8
0
% E
% Phe:
0
0
0
39
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
93
0
0
0
0
39
0
0
0
% G
% His:
0
0
8
16
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
0
16
8
% I
% Lys:
8
39
16
0
8
77
0
16
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
8
% M
% Asn:
0
0
47
0
0
0
0
8
0
0
16
0
0
0
16
% N
% Pro:
0
0
0
8
24
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
39
0
0
0
0
% Q
% Arg:
0
31
0
8
16
24
8
0
8
0
16
8
77
0
0
% R
% Ser:
0
0
8
0
8
0
0
70
8
8
16
0
0
24
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
16
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _